abstract：:It is more difficult to control humoral rejection in living donor liver transplantations (LDLT) across the ABO blood group barrier than in matched or compatible combinations. We achieved excellent results in ABO-incompatible transplantation with novel immunosuppressive regimens and plasma exchange (PE). Among 82 LDLT ...

journal_title：Transplantation proceedings

authors： Kawagishi N,Satoh K,Enomoto Y,Akamatsu Y,Sekiguchi S,Fukumori T,Fujimori K,Satomi S

更新日期：2005-03-01 00:00:00

abstract：:Alagille syndrome (AS) is a dominantly inherited, multisystem disorder involving the liver, heart, eyes, face, and skeleton. From October 1997 through July 2004, 260 pediatric orthotopic liver transplantations (OLTx) were performed in 231 patients. This report describes 21 patients of median age 1.95 years (range, 0.7...

journal_title：Transplantation proceedings

authors： Maldini G,Torri E,Lucianetti A,Guizzetti M,Pinelli D,Bertani A,Corno V,Giovanelli M,Zambelli M,Stroppa P,Alberti D,Torre G,Spada M,Gridelli B,Colledan M

更新日期：2005-03-01 00:00:00

abstract：:Liver transplantation (OLT) remains a major medical and surgical challenge in small patients. From October 1997 through July 2004, 17 babies less than 6 kg underwent 18 OLTs. Median age and weight were 3 months (range = 1 to 9) and 4.7 kg (range = 2.2 to 5.8). Two whole, one reduced, and 15 split-liver grafts (left la...

journal_title：Transplantation proceedings

authors： Lucianetti A,Guizzetti M,Bertani A,Corno V,Maldini G,Pinelli D,Aluffi A,Codazzi D,Spotti A,Spada M,Gridelli B,Torre G,Colledan M

更新日期：2005-03-01 00:00:00

abstract：:Right anterior-medial lobe congestion due to temporary clamping of segment V and/or VIII is common in the operative theater during adult donor right lobe liver transplantation, the most common procedure in our institute. We have used an autogenous saphenous vein conduit to recipient portal vein tributaries in 15 cases...

journal_title：Transplantation proceedings

authors： Moon IS,Kim DG,Lee MD,Hong SK,Park SC,Oh DY,Ahn ST,Lee YJ

更新日期：2005-03-01 00:00:00

abstract：INTRODUCTION:To evaluate the influence of pretransplantation recipient and donor prognostic factors on graft-patient survival. MATERIALS AND METHODS:Between April 1986 and June 2003, 40 liver transplantation (LT) procedures to treat fulminant hepatic failure were performed (5.7%). Twenty-one pre-LT recipient and donor...

journal_title：Transplantation proceedings

authors： Montalti R,Nardo B,Beltempo P,Bertelli R,Puviani L,Cavallari A

更新日期：2005-03-01 00:00:00

abstract：:It is still not clear whether double-J stents (DJS) are of benefit. We sought to determine whether routine prophylactic use of DJS reduced postoperative complications after renal transplantation. We prospectively evaluated 42 living donor renal transplantations performed between September 2001 and September 2003. The ...

journal_title：Transplantation proceedings

authors： Moray G,Yagmurdur MC,Sevmis S,Ayvaz I,Haberal M

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:The absolute risk of fractures in renal transplant patients is 3 times that of matched controls. Most of the symptomatic fractures are peripheral, suggesting a greater compromise of cortical bone. Peripheral quantitative computed tomography (pQCT) is a new imaging technique that allows separate noninvasive e...

journal_title：Transplantation proceedings

authors： Negri AL,Lombas C,Cuevas C,Schiavelli R,Bogado CE,Zanchetta JR

更新日期：2005-03-01 00:00:00

abstract：:The aim of this work was to study the effect of early administration of angiotensin-converting enzyme inhibitors (ACEI) and angiotensin II type-I receptors blockers (ARB) on renal function and proteinuria in renal transplant recipients with good, stable renal function and mild proteinuria. Twenty four patients started...

journal_title：Transplantation proceedings

authors： Montanaro D,Gropuzzo M,Tulissi P,Vallone C,Boscutti G,Mioni R,Risaliti A,Baccarani U,Adani GL,Sainz M,Bresadola F,Mioni G

更新日期：2005-03-01 00:00:00

abstract：INTRODUCTION:The biological behavior of most solid tumors in transplant recipients has not been adequately compared to the general population. The purpose of the present study was to compare outcomes in de novo colorectal cancer (CRC) following solid organ transplantation to those observed in the general population (SE...

journal_title：Transplantation proceedings

authors： Buell JF,Papaconstantinou HT,Skalow B,Hanaway MJ,Alloway RR,Woodle ES

更新日期：2005-03-01 00:00:00

abstract：:We looked at mycobacterial infections occurring after a kidney transplant to determine incidence, risk factors, and outcomes. Of 3921 kidney transplants performed between 1984 and 2002, 18 (0.45%) (10 men, eight women; 11 cadaveric donor, seven living donor graft) were identified as having mycobacterial infection at s...

journal_title：Transplantation proceedings

authors： Jie T,Matas AJ,Gillingham KJ,Sutherland DE,Dunn DL,Humar A

更新日期：2005-03-01 00:00:00

abstract：AIMS:Our goal was to evaluate the efficacy and safety of basiliximab (Simulect) as immunosuppressive induction therapy for the prevention of acute allograft rejection among sensitized kidney recipients. METHODS:Fifty-six adult recipients receiving cadaveric kidney transplant with panel reactive antibody class I rangin...

journal_title：Transplantation proceedings

authors： Tan J,Yang S,Wu W

更新日期：2005-03-01 00:00:00

abstract：UNLABELLED:Monitoring of cyclosporine (microemulsion CsA) at 2 hours post-dose (C2), a measure of absorption and exposure, appears superior to trough (C0) monitoring for prediction of rejection risk. The purpose of this study was to determine whether C2 was cost-effective compared to C0 in Argentina. METHODS:A predict...

journal_title：Transplantation proceedings

authors： Balshaw R,Machnicki G,Carreño CA,Toselli L,Otero A,Keown PA

更新日期：2005-03-01 00:00:00

abstract：:The aim of this study was to evaluate the impact of sirolimus and cyclosporine (CsA) combined therapy on the incidence and duration of delayed graft function (DGF), and the impact of the latter on 1-year graft function. The study entailed 23 cadaveric renal recipients treated with sirolimus-CsA-prednisone regimen (sir...

journal_title：Transplantation proceedings

authors： Boratyńska M,Banasik M,Patrzalek D,Szyber P,Klinger M

更新日期：2005-03-01 00:00:00

abstract：UNLABELLED:A primary reason to eliminate corticosteroids from immunosuppressive regimens in solid organ transplant recipients is improved cardiovascular risk profiles. Although a number of studies have documented that corticosteroid withdrawal (CSWD) regimens reduce hypertension, hyperlipidemia, diabetes, and weight ga...

journal_title：Transplantation proceedings

authors： Rogers CC,Alloway RR,Boardman R,Trofe J,Hanaway MJ,Alexander JW,Roy-Chaudhury P,Buell JF,Thomas M,Susskind B,Woodle ES

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:To investigate the expression of CD158b on peripheral blood lymphocytes after kidney transplantation. METHODS:Sixty two kidney transplant patients were divided into two groups (normal group and rejection group) according to pathologic results and clinical situation. Blood samples were assessed for percentage...

journal_title：Transplantation proceedings

authors： Kang N,Guan D,Xing N,Xia C

更新日期：2005-03-01 00:00:00

abstract：INTRODUCTION:We sought to determine whether sequential changes in chemokine ligand/receptor gene expression in the early posttransplant period of human renal allografts can be detected in peripheral blood mononuclear cells (PBMCs) and whether any such changes are predictive of clinical events. METHODS:Blood samples fr...

journal_title：Transplantation proceedings

authors： Dalton RS,Webber JN,Pead P,Gibbs PJ,Sadek SA,Howell WM

更新日期：2005-03-01 00:00:00

abstract：:The UNOS donor population was examined from 1999 to 2002, and approximately 25% of the over 23,000 donors were biopsied (Bx). There was a significant trend (P < .001) of older donors, cardiovascular accident, and hypertension in the Bx group versus the non-Bx group. The percent GS was directly correlated (P < .001) to...

journal_title：Transplantation proceedings

authors： Cicciarelli J,Cho Y,Mateo R,El-Shahawy M,Iwaki Y,Selby R

更新日期：2005-03-01 00:00:00

abstract：:Side effects of calcineurin inhibitors (CNIs) include nephrotoxicity and hypertension. Moreover, children have a higher risk of infections and posttransplantation lymphoproliferative disorders. We retrospectively evaluated the efficacy and safety of Sirolimus (SRL) in 18 patients, who were 10.52 +/- 5.03 years at time...

journal_title：Transplantation proceedings

authors： Ibáñez JP,Monteverde ML,Goldberg J,Diaz MA,Turconi A

更新日期：2005-03-01 00:00:00

abstract：:Hepatitis C viremia occurs universally after liver transplantation. It is speculated that soluble HCV proteins may be immunomodulatory. We measured the effects of HCV core upon human T-cell proliferation, expression of activation markers, and interaction with cyclosporine. Cells were activated with anti-CD3 for 2-6 da...

journal_title：Transplantation proceedings

authors： Kimball P,Verbeke S,Shiffman M

更新日期：2005-03-01 00:00:00

abstract：INTRODUCTION:Laparoscopic donor nephrectomy (LDN) involving kidneys with multiple arterial vessels is limited to a small number of reports, with all but two series reporting fewer than 25 patients. Moreover, outside of the pioneering centers at the University of Maryland and Johns Hopkins, no series of at least 25 pati...

journal_title：Transplantation proceedings

authors： Husted TL,Hanaway MJ,Thomas MJ,Woodle ES,Buell JF

更新日期：2005-03-01 00:00:00

abstract：INTRODUCTION:Several living donor kidney exchange programs (LDKEPs) have been established throughout the world; however, none have yet achieved the perceived substantial potential for increasing the number of living donor kidney transplants. Over the past 2 years, the Ohio Solid Organ Transplant Consortium (OSOTC) has ...

journal_title：Transplantation proceedings

authors： Woodle ES,Bohnengel A,Boardman R,Downing K,Ohio Solid Organ Transplant Consortium Kidney Committee.

更新日期：2005-03-01 00:00:00

abstract：:From 1993 to 2003 there have been significant changes in the number and demographics of deceased donors referred to the organ procurement organization (OPO) in the state of Michigan (USA). It was the aim of this study to document the magnitude of these changes and attempt to explain them. There has been a 26-fold incr...

journal_title：Transplantation proceedings

authors： Rosenberg JC,Beyersdorf T,Pietroski R

更新日期：2005-03-01 00:00:00

abstract：AIM:To clarify the decision-making and bereavement needs of family members who had organ donation discussed with them; to provide a rationale for further preparation of professionals involved in this sensitive work. METHODS:This work used a 3-year longitudinal design. A sample of 49 family members who had donation dis...

journal_title：Transplantation proceedings

authors： Sque M,Long T,Payne S

更新日期：2005-03-01 00:00:00

abstract：INTRODUCTION:Expression of human complement regulatory proteins (CRP) on pig endothelial cells (PEC) has been useful to avoid hyperacute rejection by human sera. On the other hand, porcine endogenous retrovirus (PERV) from PEC transfectants with CRP may acquire resistance to human sera. In this study, we investigated t...

journal_title：Transplantation proceedings

authors： Hazama K,Miyagawa S,Yamamoto A,Kubo T,Miyazawa T,Tomonaga K,Watanabe R,Okumura M,Matsuda H,Shirakura R

更新日期：2005-01-01 00:00:00

abstract：INTRODUCTION:In a discordant orthotopic xenotransplantation model (pig-to-baboon) donor pigs expressing human decay accelerating factor (hDAF) as a regulator of complement activity were used to prevent hyperacute xenograft rejection (HXR). We investigated a modified immunosuppressive therapy consisting of ERL080 (Novar...

journal_title：Transplantation proceedings

authors： Brenner P,Schmoeckel M,Wimmer C,Eder V,Rucker A,Felbinger T,Uchita S,Hinz M,Brandl U,Meiser B,Reichenspurner H,Hammer C,Reichart B

更新日期：2005-01-01 00:00:00

abstract：INTRODUCTION:The protective role of nitric oxide (NO) against hepatic ischemia-reperfusion (I/R) injury remains controversial. In this study we investigated the effect of tetrahydrobiopterin (BH4) on the survival of rats exposed to an hepatic I/R injury. METHODS:The rats were subjected to 100 minutes of 70% hepatic is...

journal_title：Transplantation proceedings

authors： Hara Y,Teramoto K,Kumashiro Y,Sato E,Nakamura N,Takatsu S,Kawamura T,Arii S

更新日期：2005-01-01 00:00:00

abstract：:We investigated the effects of portocaval shunt (PCS) on excessive portal flow in producing sinusoidal microcirculatory injury in small-for-size liver transplants in pigs. The posterior segment of a whole liver (25%) was transplanted orthotopically. The pigs were divided two groups: group A, graft with PCS (n = 11), a...

journal_title：Transplantation proceedings

authors： Wang HS,Enomoto Y,Usuda M,Miyagi S,Asakura T,Masuoka H,Fukushima K,Aiso T,Narita T,Yamaya H,Sekiguchi S,Kawagishi N,Sato A,Ohkohchi N,Satomi S

更新日期：2005-01-01 00:00:00

abstract：UNLABELLED:Ischemic preconditioning (IP) has been shown to ameliorate renal ischemia reperfusion injury. Using a rat kidney transplantation model we determined if IP improves graft function after prolonged cold storage. MATERIALS AND METHODS:Syngeneic rat kidneys were divided into two groups. Prior to 42 hours of cold...

journal_title：Transplantation proceedings

authors： Fuller TF,Freise CE,Feng S,Niemann CU

更新日期：2005-01-01 00:00:00

abstract：:Perfusion parameters (PP) and early transplant outcome data from 332 consecutive ECD type kidneys machine preserved on the Waters RM-3 apparatus were reviewed and analyzed to examine the validity of using suboptimal PPs (renal resistance of .41-.60) as a criterion for discarding kidneys. Overall discard rate was 23.5%...

journal_title：Transplantation proceedings

authors： Mozes MF,Skolek RB,Korf BC

更新日期：2005-01-01 00:00:00

abstract：INTRODUCTION:A prospective, randomized, multicenter, open clinical trial was performed to compare the main liver function tests, postoperative complications, and early graft and patient survival of recipients transplanted with livers preserved in Celsior (CEL) versus histidine tryptophan ketoglutarate (HTK) solutions. ...

journal_title：Transplantation proceedings

authors： Nardo B,Bertelli R,Montalti R,Beltempo P,Puviani L,Pacilè V,Cavallari A

更新日期：2005-01-01 00:00:00

abstract：:We previously reported that mouse embryonic stem (ES) cells are capable of differentiating into hepatocytes in cultured embryoid bodies (EBs) and that hepatocytes generate in the recipient liver injected with cultured day-9 EB cells via spleen without the formation of a teratoma. Because ES cells frequently form terat...

journal_title：Transplantation proceedings

authors： Teramoto K,Hara Y,Kumashiro Y,Chinzei R,Tanaka Y,Shimizu-Saito K,Asahina K,Teraoka H,Arii S

更新日期：2005-01-01 00:00:00

abstract：:One hundred fifty million people suffer from diabetes mellitus worldwide. Modern exogenous insulin therapy cannot prevent late complications. Islet cell transplantation could be a sufficient therapeutic option but the shortage of human organs limits this option. The use of xenogeneic porcine islet cells may also be a ...

journal_title：Transplantation proceedings

authors： Schaffellner S,Stadlbauer V,Stiegler P,Hauser O,Halwachs G,Lackner C,Iberer F,Tscheliessnigg KH

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Recently, preservation using oxygenated perfluorocarbon (the two-layer method) has shown beneficial effects on islet yield and viability. In this paper, we apply this concept on isolation processes to examine the effectiveness of oxygenation. METHODS:Rat pancreata were digested using four different methods:...

journal_title：Transplantation proceedings

authors： Tanioka Y,Tanaka T,Gotoh T,Kakinoki K,Li S,Yoshikawa T,Sakai T,Fujino Y,Suzuki Y,Kuroda Y

更新日期：2005-01-01 00:00:00

abstract：:To assess survival of grafts after uncontrollable rejection, one performs backtransplantation from the recipient to the donor. This study investigated backtransplantation in an animal model. Hearts were transplanted heterotopically in rats. After a few days, the transplanted heart grafts were harvested from the recipi...

journal_title：Transplantation proceedings

authors： Yuzawa K,Fukunaga K,Ohkohchi N

更新日期：2005-01-01 00:00:00

abstract：UNLABELLED:Organ rejection and inflammation are accompanied by endothelial cell activation. An in vitro model with patient-specific endothelial cells was used to study the impact of mTOR inhibitors on cell growth and release of proinflammatory cytokines. MATERIAL AND METHODS:Confluent monolayers of human saphenous vei...

journal_title：Transplantation proceedings

authors： Lehle K,Birnbaum DE,Preuner JG

更新日期：2005-01-01 00:00:00

abstract：:This study including prevention and rescue experiments was performed to examine the efficacy of FK778 and its interactions with FK506. In the prevention experiment, Brown-Norway rats transplanted with a 7 Lewis livers received day-course of FK778 or a combination of FK778 and FK506 treatment. For the rescue experiment...

journal_title：Transplantation proceedings

authors： Yamamoto S,Okuda T,Yamasaki K,Tanaka H,Takemura S,Minamiyama Y,Ikeda K,Hirohashi K,Suehiro S

更新日期：2005-01-01 00:00:00

abstract：:Warm and cold ischemia as well as rejection of the transplanted organ or tissue cause destructive changes in the graft parenchyma. Fragments of disintegrated cellular organelles are phagocytized and digested by recipient scavenger cells in lymph nodes, spleen, and liver. Some fragments engulfed by dendritic cells are ...

journal_title：Transplantation proceedings

authors： Interewicz B,Olszewski WL,Stanislawska J,Sikora M,Durlik M,Maksymowicz M

更新日期：2005-01-01 00:00:00

abstract：:In prior experiments, we found that recipients, even though specifically tolerant of donor antigens, will develop striking cardiac allograft vasculopathy (CAV) in allogeneic mouse heart transplants. This suggested that innate immune responses, in addition to conventional adaptive immunity, may be involved in the devel...

journal_title：Transplantation proceedings

authors： Uehara S,Chase CM,Colvin RB,Russell PS,Madsen JC

更新日期：2005-01-01 00:00:00

abstract：:CD4(+)CD25(+) regulatory T cells are selected in the thymus to control autoreactive thymic escapees preventing autoimmunity that cannot be achieved by negative selection or deletion alone, thus playing an important role in the maintenance of immunological homeostasis. Not only significant in preventing autoimmunity, C...

journal_title：Transplantation proceedings

authors： Tamura S,Beck Y,Ando Y,Tahara H

更新日期：2005-01-01 00:00:00

abstract：:Specialized antigen-presenting cells (APC), known as dendritic cells (DC), play a pivotal role in initiating primary immune responses. Several vector systems, including adenoviral vectors, retroviral vectors, hemagglutinating virus of Japan-related vectors, and the electroporation, have been shown to transduce genes i...

journal_title：Transplantation proceedings

authors： Satoh E,Yan H,Miyagi T,Li XK,Sugiura W,Yamamoto N,Teramoto K,Arii S,Kimura H

更新日期：2005-01-01 00:00:00